A must-see when you visit Panama : Casco Viejo.
Casco Viejo is a historic distric of Panama City and a World Heritage UNESCO site. Completed and settled in 1673, it was built following the near-total destruction of the original Panamá city, Panamá Viejo in 1671, when the latter was attacked by pirates.
This old town is also the upscale area of the city with great nightlife spots. We spent almost every night out in Casco Viejo (Tantalo Kitchen, DiVino Enoteca, American Trade Hotel) and it was such a pleasure to enjoy walking around, enjoying the beautiful colonial architecture and an unusual blend of Spanish, French and early American styles.
Note that this is quite a touristic area but it doesn’t get too crowded, there are nice stores where you can get a reasonably priced Panama hat and souvenirs, enjoy delicious food at the fusion-style restaurants and lounges.
After dark it is even more alive, clubs and bars open till dawn, this area is also the spot for expats. Just go with the flow start with dinner at the Il Carpaccio italian/latin fusion cuisine then head to the Tantalo rooftop for drinks. If you like to party just follow the music in the street you will find pretty cool clubs and dancing bars.
Quick tip : if you’re hungry after a late night, the Hilton hotel downtown hits the spot!